Acetylsalicylic acid

Research use only, not for human use.

Aspirin (Acetylsalicylic acid) is a potent and selective inhibitor of cyclooxygenase (COX) with a broad range of pharmacological activities including anti-inflammation and pain relief.

Aspirin (Acetylsalicylic acid) is a potent and selective inhibitor of cyclooxygenase (COX) with a broad range of pharmacological activities including anti-inflammation and pain relief. Multiple studies have accumulated sufficient evidence to establish the association between the use of aspirin and a reduced risk of Ys including prostate Y, breast Y, colorectal Y, endometrial Y, and ovarian Y. Aspirin suppresses ovarian Y cells harboring COX-1 by acting as histone deacetylase inhibitors to up-regulate cell cycle arrest protein p21. Aspirin also inhibits the expression of COX-2 in human umbilical vein endothelial cells and neonatal rat ventricular cardiomyocytes resulting in reduced PG production and the down-regulation of ERK and NF-KB respectively.

Acetylsalicylic Acid

Chromatin/Epigenetic

COX

COX-1; COX-2

Inflammation/Immunology

——

50-78-2

180.16

C9H8O4

>98%(HPLC)

Ethanol: 36 mg/mL (199.82 mM); DMSO: 36 mg/mL (199.82 mM)

O=C(O)C1=CC=CC=C1OC(C)=O

Benzoic acid, 2-(acetyloxy)-

(-20℃)

With Ice Pack

≥ 2 years